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Excorp Medical's Bioartificial Liver System comprises a reusable instrument, disposable tubing set and the proprietary, disposable bioartificail reactor.Once approved by regulatory agencies, Excorp Medical expects this breakthrough Bioartificial Liver System technology to be both live-saving and cost effective.Certain drugs or machines are available to substitute temporarily or long-term for many organs in the body…  no comparable substitute has been developed for the liver.The liver is the largest organ in the body and performs a variety of tasks impacting all body systems… as a result liver disease has widespread effects on virtually all other organs.Excorp Medical is currently the only company approved to conduct bioartificial liver human trials within the U.S.Currently patients must receive a liver transplant or endure prolonged hospitalization at great expense to have a chance at survival.Excorp Medical Bioartificial Liver System treatments serve as a bridge to liver regeneration and transplantExcorp Medical has developed a Bioartificial Liver System for the metabolic support of patients with compromised liver function.
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ARTICLES
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Pre-clinical Evaluation of Bioartificial Liver Support System
Plasma versus Whole Blood Perfusion
First Clinical Use of a Novel Bioartificial Liver Support
Clinical and laboratory evaluation of the safety
Bound Dilute Analysis
Oxygen Consumption in a Hollow Fiber Bioartificial Liver - Revisited

Published Articles

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Oxygen Consumption in a Hollow Fiber Bioartifical Liver - Revisited
2004 International Society of Artificial Organs,
Blackwell Publishing, Inc.
By John F. Patzer II

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Bound Solute Dialysis
ASAIO Journal 2003,
By John Patzer & Steve Benet

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Clinical and Laboratory Evaluation of the Safety of a Bioartificial Liver Assist Device for Potential Transmission of Porcine Endogenous Retrovirus
Published in Transplantation 2002 Lippincott Williams & Wilkins, Inc.
By: Kuddus, R.; Patzer, J.J. II.; Lopez, R.; Mazariegos, G.V.; Meighen, B.; Kramer, D.J.; Rao, A.S.

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First Clinical Use of a Novel Bioartificial Liver Support
American Journal of Transplantation 2002
By George V. Mazariegos, John F. Patzer II , Roberto C. Lopez, Maricio Giraldo, Michael E. deVera, Tracy A. Grogan, Yue Zhu, Melissa L. Fulmer, Bruce P.Amiot, and David I. Kramer

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Plasma versus Whole Blood Perfusion in a Bioartificial Liver Assist Device
ASAIO Journal 2002
By John F. Patzer II, Brian Campbell, and Richard Miller

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Pre-clinical Evaluation of the Excorp Medical, Inc., Bioartificial Liver Support System - American College of Surgeons 2002
By John F. Patzer II, Ph.D., George V. Mazariegos, MD, FACS & Roberto Lopez, MD, Bioartificial Liver Program Investigators, Univeristy of Pittsburgh

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